Comparative analysis using the draft genome sequence of California poppy (<i>Eschscholzia californica</i>) for exploring the candidate genes involved in benzylisoquinoline alkaloid biosynthesis

ABSTRACT Genome characterization of California poppy (Eschscholzia californica cv. “Hitoezaki”), which produces pharmaceutically important benzylisoquinoline alkaloids (BIAs), was carried out using the draft genome sequence. The numbers tRNA and rRNA genes were close to those other plant species tested, whereas frequency repetitive sequences distinct from species. Comparison predicted with Amborella trichopoda, Nelumbo nucifera, Solanum lycopersicum, Arabidopsis thaliana, analyses gene ontology Kyoto Encyclopedia Genes Genomes pathway indicated that enzyme involved in BIA biosynthesis highly enriched genome. Further comparative analysis information Papaver somniferum Aquilegia coerulea, both BIA-producing plants, revealed many encoding biosynthetic enzymes, transcription factors, transporters, candidate proteins, possibly related biosynthesis, specifically distributed these